CREAFEM FOOD CONSULTING®
Creation and development strategic,competitive and value-added food products.
Jan 8, 2013
Dec 28, 2012
HAPPY HOLIDAYS !
Happy Holidays from CREAFEM FOOD CONSULTING®, with wishes
for a safe and prosperous New Year.
Nov 26, 2012
Nov 20, 2012
BOTULISM-CLOSTRIDIUM BOTULINUM
Botulism is a rare but serious paralytic illness caused by a nerve toxin that is produced by the bacterium Clostridium botulinum and sometimes by strains of Clostridium butyricum and Clostridium baratii.
There are five main kinds of botulism. Foodborne botulism is caused
by eating foods that contain the botulinum toxin. Wound botulism is
caused by toxin produced from a wound infected with Clostridium botulinum.
Infant botulism is caused by consuming the spores of the botulinum
bacteria, which then grow in the intestines and release toxin. Adult
intestinal toxemia (adult intestinal colonization) botulism is a very
rare kind of botulism that occurs among adults by the same route as
infant botulism. Lastly, iatrogenic botulism can occur from accidental
overdose of botulinum toxin. All forms of botulism can be fatal and are
considered medical emergencies. Foodborne botulism is a public health
emergency because many people can be poisoned by eating a contaminated
food.
Clostridium botulinum is the name of a group of bacteria. They
can be found in soil. These rod-shaped organisms grow best in low
oxygen conditions. The bacteria form spores which allow them to survive
in a dormant state until exposed to conditions that can support their
growth. There are seven types of botulism toxin designated by the
letters A through G; only types A, B, E and F cause illness in humans.
The classic symptoms of botulism include double vision, blurred vision,
drooping eyelids, slurred speech, difficulty swallowing, dry mouth,
and muscle weakness. Infants with botulism appear lethargic, feed
poorly, are constipated, and have a weak cry and poor muscle tone.
These are all symptoms of the muscle paralysis caused by the bacterial
toxin. If untreated, these symptoms may progress to cause paralysis of
the respiratory muscles, arms, legs, and trunk. In foodborne
botulism, symptoms generally begin 18 to 36 hours after eating a
contaminated food, but they can occur as early as 6 hours or as late as
10 days.
The respiratory failure and paralysis that occur with severe botulism
may require a patient to be on a breathing machine (ventilator) for
weeks or months, plus intensive medical and nursing care. The
paralysis slowly improves. Botulism can be treated with an antitoxin
which blocks the action of toxin circulating in the blood.If given before paralysis is complete, antitoxin can
prevent worsening and shorten recovery time. Physicians may try to
remove contaminated food still in the gut by inducing vomiting or by
using enemas. Wounds should be treated, usually surgically, to remove
the source of the toxin-producing bacteria followed by administration
of appropriate antibiotics. Good supportive care in a hospital is the
mainstay of therapy for all forms of botulism.
Many cases of botulism are preventable. Foodborne botulism has often
been from home-canned foods with low acid content, such as asparagus,
green beans, beets and corn and is caused by failure to follow proper
canning methods. However, seemingly unlikely or unusual sources are
found every decade, with the common problem of improper handling during
manufacture, at retail, or by consumers; some examples are chopped
garlic in oil, canned cheese sauce, chile peppers, tomatoes, carrot
juice, and baked potatoes wrapped in foil. In Alaska, foodborne
botulism is caused by fermented fish and other aquatic game foods.
Persons who do home canning should follow strict hygienic procedures to
reduce contamination of foods, and carefully follow instructions on
safe home canning including the use of pressure canners/cookers as
recommended through county extension services or from the US Department
of Agriculture. Oils infused with garlic or herbs should be
refrigerated. Potatoes which have been baked while wrapped in aluminum
foil should be kept hot until served or refrigerated. Because the
botulinum toxin is destroyed by high temperatures, persons who eat
home-canned foods should consider boiling the food for 10 minutes
before eating it to ensure safety. Wound botulism can be prevented by
promptly seeking medical care for infected wounds and by not using
injectable street drugs. Most infant botulism cases cannot be prevented
because the bacteria that causes this disease is in soil and dust. The
bacteria can be found inside homes on floors, carpet, and countertops
even after cleaning. Honey can contain the bacteria that causes infant
botulism so, children less than 12 months old should not be fed honey.
Honey is safe for persons 1 year of age and older.
(From CDC)
Nov 11, 2012
Nov 10, 2012
SAFE INTERNAL COOKING TEMPERATURES CHART
| Food | Temperature |
|---|---|
| Beef, veal and lamb (pieces and whole cuts) | |
| Medium-rare | 63°C (145°F) |
| Medium | 71°C (160°F) |
| Well done | 77°C (170°F) |
| Pork | |
| Pork (pieces and whole cuts) | 71°C (160°F) |
| Poultry (for example, chicken, turkey, duck) | |
| Pieces | 74°C (165°F) |
| Whole | 85°C (185°F) |
| Ground meat and meat mixtures (for example, burgers, sausages, meatballs, meatloaf, casseroles) | |
| Beef, veal, lamb and pork | 71°C (160°F) |
| Poultry | 74°C (165°F) |
| Egg | |
| Egg dishes | 74°C (165°F) |
| Others | |
| Others (for example, hot dogs, stuffing, leftovers, seafood) | 74°C (165°F) |
| Game | |
| Ground venison, sausage, and bologna | |
| Ground venison, sausage, and bologna | 74°C (165°F) |
| Chops, steaks, and roasts of fresh venison (e.g., deer, elk, moose, caribou/reindeer, antelope and pronghorn) | |
| Medium rare | 63°C (145°F) |
| Medium | 71°C (160°F) |
| Well done | 77°C (170°F) |
| Bear, bison, musk-ox , and walrus | |
| Bear, bison, musk-ox , and walrus | 74°C (165°F) |
| Small game | |
| Small game (e.g., rabbit) | 71°C (160°F) |
| Game birds/waterfowl | |
| Game bird/waterfowl whole (e.g., wild turkey, duck and goose partridge, and pheasant,) | 82°C (180°F) |
| Breasts and roasts of all game birds and waterfowl | 77°C (170°F) |
| Thighs, wings | 82°C (180°F) |
| Stuffing (cooked alone or in bird) | 74°C (165°F) |
| Fish | |
| Fish | 70°C (158°F) |
| Shrimp, lobster, and crab | |
| Shrimp, lobster, and crab | 70°C (158°F) |
| Scallops | |
| Scallops | 70°C (158°F) |
| Clams, mussels, and oysters | |
| Clams, mussels, and oysters | 70°C (158°F) |
SALMONELLA
Salmonella bacteria are found naturally in the intestines of animals, reptiles and birds. The bacteria are usually transmitted to people when they eat foods contaminated with animal feces (stool). Contaminated foods often come from animal sources, like poultry, beef, milk or eggs. But all foods, including fruits and vegetables, can become contaminated. It is important to remember that foods that are contaminated with bacteria can have a completely normal appearance. This is why it is important to always use safe food handling techniques.
People who eat food contaminated by Salmonella can become ill with salmonellosis. The disease is more common in summer than in winter. Like other foodborne illnesses, the symptoms of salmonellosis can feel like stomach flu, but they can also develop into serious illness with long-lasting effects.
How do people get sick?
Did you know?
Intestinal illness can be caused by viruses, bacteria or parasites, and usually involves vomiting and diarrhea. People often call it the flu, though it is in no way related to the influenza virus, which causes respiratory illness.
Both animals and people can be carriers of Salmonella. They can then spread the bacteria to foods, surfaces, other animals or people. Food can become contaminated with Salmonella during butchering, when food is handled by a person infected with Salmonella, or from cross-contamination when raw foods or pets are handled improperly.Intestinal illness can be caused by viruses, bacteria or parasites, and usually involves vomiting and diarrhea. People often call it the flu, though it is in no way related to the influenza virus, which causes respiratory illness.
The most common way of getting salmonellosis is by eating contaminated foods that have not been cooked properly. Common sources of Salmonella include:
- raw and undercooked meat (especially poultry)
- raw or undercooked eggs
- homemade salad dressings, hollandaise sauce, mayonnaise, ice cream, cookie dough, tiramisu and frostings
- raw fruits and vegetables (especially sprouts and cantaloupes) and their juices
- unpasteurized dairy products, like raw milk and raw milk cheeses, cream-filled deserts and toppings
- pet treats
- fish and shrimp
- not washing fresh fruits and vegetables before eating them
- not thoroughly cleaning work surfaces used to prepare raw meat and other foods
- not washing your hands with soap after handling raw meat or using the bathroom
- not washing your hands with soap after handling pets, especially those with diarrhea or exotic pets like snakes, turtles and reptiles
What are the symptoms and treatment?
People infected with Salmonella can experience a wide range of symptoms. Some do not get sick at all, though they can still spread the infection to others. Others feel as though they have a bad case of the flu. Still others become seriously ill and must be hospitalized.Most people with salmonellosis develop the following symptoms 6 to 72 hours after being infected:
- fever
- chills
- diarrhea
- abdominal cramps
- headache (with sudden onset)
- nausea
- vomiting (sometimes)
In a small number of cases, Salmonella may spread from the intestines to the blood stream and other body sites, causing severe illness and, in vulnerable people, death. In cases of severe illness, patients may be treated with antibiotics. However, some Salmonella bacteria have become resistant to many commonly used antibiotics.
A small number of infected people go on to develop chronic pains in their joints, irritation of the eyes and painful urination, a condition called Reiter's Syndrome. It can last for months or years, sometimes leading to chronic arthritis, which is difficult to treat.
Because many different illnesses cause the same symptoms as salmonellosis, the only way to diagnose it is through laboratory tests on the stools of infected people. Once Salmonella bacteria have been identified, further testing can determine the type of Salmonella and the appropriate antibiotics to use in treatment.
How do I avoid getting sick?
Food safety tip
When cooking a chicken or turkey, it is safest to cook the
stuffing in a separate dish, to prevent cross-contamination and
undercooking.These tips will help protect you and your family from Salmonella:
- Cook food to a safe internal temperature using a digital thermometer.
- Poultry and meat, including hamburgers, should be well cooked, not pink in the middle. If you are served undercooked food in a restaurant, send it back.
- Do not eat raw or undercooked eggs. Raw eggs may be found in homemade foods like hollandaise sauce, Caesar and other salad dressings, tiramisu, ice cream, mayonnaise, cookie dough and frostings.
- Only buy clean and uncracked eggs. Store eggs in their original carton (so you can check the "best before" date) and place them in the coldest section of the fridge, not the door.
- Eat and drink only pasteurized juice, cider, milk and milk products. Mother's milk is the safest food for infants. Breastfeeding prevents salmonellosis and many other health problems.
- When buying and storing groceries, keep meats separate from fruits, vegetables, cooked foods and ready-to-eat foods. If you use reusable grocery bags and bins, make sure to clean them often with hot, soapy water.
- Wash your hands before handling any food. Be sure to wash your hands, cutting boards, counters, knives and other utensils after preparing raw foods.
- Wash raw fruits and vegetables thoroughly with clean, safe running water before you prepare and eat them. Use a brush to scrub produce with firm or rough surfaces, like oranges, cantaloupes, potatoes and carrots.
- Never place cooked food on the unwashed plate that held raw meat, poultry or fish. Wash thermometers in between testing.
- Wash your hands after contact with animal feces (for example, after changing kitty litter or scooping up after your dog).
- Since reptiles can have Salmonella, always wash your hands after handling them. Reptiles, including turtles, are not good pets for children and should not be in the same house as an infant.
- Keep pets away from food storage and preparation areas. Wash your hands well with soap and water after handling pet treats, pet food and pet toys, or after playing with or cleaning up after your pet.
- If you have been diagnosed with salmonellosis or any other gastrointestinal illness, do not prepare food or pour water for other people.
- If you are diagnosed with salmonellosis, be sure that you or your doctor tells the local Public Health Department. If many cases happen at the same time, it may mean that a restaurant or a particular food item has a problem that needs to be corrected.
Nov 5, 2012
Nov 3, 2012
Oct 25, 2012
TAKE FOLIC ACID BEFORE YOU GET PREGNANT
Before you get pregnant you need an adequate folic acid intake. This
reduces the risk for certain birth defects, such as spina bifida. To
achieve the preventive effect, start taking folic acid dietary
supplements one month prior to conception. Folic acid supplements are
available at for example drug stores and grocery stores.
Today folic acid intakes below recommendations are common among women. Many pregnancies are not planned and all women who may get pregnant are therefore recommended to take folic acid supplements.
Folate, or folic acid, is essential for cell division. During early pregnancy, the cell division of the foetus is more frequent and the need for folate, or folic acid, therefore the greatest. If you have low levels of folate in the blood, the risk is greater for your child to get certain birth defects (spina bifida). Therefore, the National Food Administration recommends anyone who may get pregnant to take supplements containing 400 micrograms of folic acid daily until the twelfth week of pregnancy. Folate and folic acid are different forms of the same B vitamin. Folate occurs naturally in foods. Folic acid is artificially produced and is used for fortification and in dietary supplements. The best sources of natural folate are dark green leafy vegetables and different kinds of cabbage, beans, lentils, root vegetables and berries.
(The National Food Agency-Sweden)
Today folic acid intakes below recommendations are common among women. Many pregnancies are not planned and all women who may get pregnant are therefore recommended to take folic acid supplements.
Folate, or folic acid, is essential for cell division. During early pregnancy, the cell division of the foetus is more frequent and the need for folate, or folic acid, therefore the greatest. If you have low levels of folate in the blood, the risk is greater for your child to get certain birth defects (spina bifida). Therefore, the National Food Administration recommends anyone who may get pregnant to take supplements containing 400 micrograms of folic acid daily until the twelfth week of pregnancy. Folate and folic acid are different forms of the same B vitamin. Folate occurs naturally in foods. Folic acid is artificially produced and is used for fortification and in dietary supplements. The best sources of natural folate are dark green leafy vegetables and different kinds of cabbage, beans, lentils, root vegetables and berries.
(The National Food Agency-Sweden)
Oct 15, 2012
WARNING ON YOUNG PEOPLE AND ENERGY DRINKS
The Belgian government's top health advisors have warned about the risks of energy drinks especially for young people.
The Conseil Supérieur de la Santé (Higher Health Council) said that
consuming energy drinks, which it noted were popular among young people,
could pose a risk to health.
The Council pointed to some of the most significant risks linked to energy drinks, starting with their contribution to an increasing overconsumption of caffeine, leading to signs of overdose and addiction.
The drinks put the consumer at high risk when combined with intense effort, such as sport.
These products also reduce the signs of drunkeness and alter the perception of a drunken state when combined with alcoholic drinks.
In its report the Council goes on to point to a catalogue of risks linked to frequent or significant consumption, which it aims to bring to the attention of the public, particularly the young, "who are particularly exposed to the marketing strategies of the relevant firms."
In the absence of a harmonised approach at EU level, which the Council says is desirable, it recommends people limit the amount and frequency of consumption so that they do not exceed 400 mg - or even 300 mg - of total caffeine intake a day.
It also recommends that people do not mix energy drinks with alcohol drinks and intense physical activity.
Pregnant and breastfeeding women and the under 16s should avoid energy drinks, as should those sensitive to caffeine.
(EU Food Law)
The Council pointed to some of the most significant risks linked to energy drinks, starting with their contribution to an increasing overconsumption of caffeine, leading to signs of overdose and addiction.
The drinks put the consumer at high risk when combined with intense effort, such as sport.
These products also reduce the signs of drunkeness and alter the perception of a drunken state when combined with alcoholic drinks.
In its report the Council goes on to point to a catalogue of risks linked to frequent or significant consumption, which it aims to bring to the attention of the public, particularly the young, "who are particularly exposed to the marketing strategies of the relevant firms."
In the absence of a harmonised approach at EU level, which the Council says is desirable, it recommends people limit the amount and frequency of consumption so that they do not exceed 400 mg - or even 300 mg - of total caffeine intake a day.
It also recommends that people do not mix energy drinks with alcohol drinks and intense physical activity.
Pregnant and breastfeeding women and the under 16s should avoid energy drinks, as should those sensitive to caffeine.
(EU Food Law)
Oct 11, 2012
Oct 8, 2012
Sep 20, 2012
Jul 25, 2012
Jul 6, 2012
GUIDELINE DAILY AMOUNTS-GDA LABEL
The GDA label shows the number of calories and grams of sugars, fat,
saturates (saturated fat) and salt per portion of food, and expresses
these quantities as a percentage of your Guideline Daily Amount.
Usually labels contain five icons, which are for calories, sugars, fat, saturates (saturated fat) and salt – always appearing in the same order.
GDAs for different Nutrients
Usually labels contain five icons, which are for calories, sugars, fat, saturates (saturated fat) and salt – always appearing in the same order.
GDAs for different Nutrients
Guideline Daily Amount
Values
|
|||
Typical values
|
Women
|
Men
|
Children (5-10 years)
|
Calories
|
2,000 kcal
|
2,500 kcal
|
1,800 kcal
|
Protein
|
45 g
|
55 g
|
24 g
|
Carbohydrate
|
230 g
|
300g
|
220 g
|
Sugars
|
90 g
|
120 g
|
85 g
|
Fat
|
70 g
|
95 g
|
70 g
|
Saturates
|
20 g
|
30 g
|
20 g
|
Fibre
|
24 g
|
24 g
|
15 g
|
Salt
|
6 g
|
6 g
|
4 g
|
OMEGA-3
the long-chain polyunsaturated omega-3 fatty acids docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA). Epidemiological studies and randomized controlled trials suggest that increased dietary intake of DHA and EPA reduce risk for cardiovascular disease via multiple mechanisms: lowering LDL cholesterol, preventing the arrhythmias that lead to sudden cardiac death, decreasing thrombosis risk, slowing the growth of atherosclerotic plaque, improving vascular endothelial function, slightly lowering blood pressure and reducing inflammation.The American Heart Association, recommends patients with documented coronary heart disease consume 1 gram of EPA and DHA per day, and that those lowering triglycerides increase the dose to 2 to 4 grams daily, whether from food sources like fatty fish or supplements administered under a physician’s direction.
Higher up on the body, DHA is a major structural and functional component of cells in the eyes and brain, where it plays a part in visual and neurological maintenance as we age. A cohort of the Framingham Heart Study found that subjects in the highest quartile for plasma concentrations of DHA had a 47% decreased risk for all dementia and a 39% decreased risk for Alzheimer’s compared to those in the bottom three quartiles. Meanwhile, a 2009 National Eye Institute study using Age-Related Eye Disease Study data revealed that participants reporting the highest dietary levels of omega-3s were 30% less likely than their lower-level counterparts to develop macular degeneration over a 12-year period.
Higher up on the body, DHA is a major structural and functional component of cells in the eyes and brain, where it plays a part in visual and neurological maintenance as we age. A cohort of the Framingham Heart Study found that subjects in the highest quartile for plasma concentrations of DHA had a 47% decreased risk for all dementia and a 39% decreased risk for Alzheimer’s compared to those in the bottom three quartiles. Meanwhile, a 2009 National Eye Institute study using Age-Related Eye Disease Study data revealed that participants reporting the highest dietary levels of omega-3s were 30% less likely than their lower-level counterparts to develop macular degeneration over a 12-year period.
May 24, 2012
NEW INGREDIENTS
Sugar Without the Calories
Swerve,
an all-natural zero-calorie sweetener made with erythritol and
oligosaccharides, was offered on the show floor in some tasty
prototypes, including a maple-nut cupcake. The sweetener browns and
caramelizes like sugar, which it can replace 1:1.
NEW INGREDIENTS
Luo Han Guo
All-natural, zero-calorie sweeteners like luo han guo (monk fruit) are all the rage. Amax NutraSource was on hand to discuss its version, Perfecta™, which is made with luo han guo extract, can be labeled as 100% natural, doesn’t contain any added flavors, and is non-GMO.
NEW INGREDIENTS
Rye Grass Pollen
Although flower pollen extract has
commonly been used in dietary supplements to aid prostate health and
urinary support—important to many aging consumers—an ingredient offered
on show floor by Graminex, made from rye grass flower pollen, is fully water-soluble and suited to use in beverages, as well as foods.
NEW INGREDIENTS
Bergamot's Cholesterol Control
Bergamot, known widely as the defining flavor in Earl Grey tea, was represented on the show floor by HP Ingredients.
The compounds melitidine and brutelidine in bergamot juice and extract
have been shown to help reduce LDL cholesterol and triglycerides while
boosting HDL levels.
May 9, 2012
PROBIOTICS MAY HELP PREVENT DIARRHEA DUE TO ANTIBIOTIC USE
Eating yogurt or taking a so-called probiotic when you have to take antibiotics may help prevent the diarrhea that often accompanies antibiotic treatment.
That’s the conclusion of a study just published in the Journal of the American Medical Association. A team of California-based researchers combined the results of 63 randomized trials pitting probiotics versus placebo among almost 12,000 men and women taking antibiotics. Those who took antibiotics plus probiotics were 42% less likely to develop diarrhea as those who got the placebo.
About one in three people who take antibiotics develop diarrhea. The symptoms usually start on the last day or two of antibiotic therapy, or a day or so after it has ended. The diarrhea is usually mild, with two to four loose stools per a lasting for a couple days. In most cases, it gets better quickly without treatment. That said, antibiotic-associated diarrhea makes some people very sick. The most severe form, called C. difficile colitis, can be life threatening.
Probiotics are live bacteria, yeast, and other microbes thought to be beneficial to human health. They’ve been widely promoted as a way to keep your body in balance. The evidence for many of these claims is slim. Perhaps the strongest evidence a benefit of probiotics is for antibiotic-associated diarrhea.
Antibiotics kill these “good” microbes along with bacteria that are causing an infection. This upsets the balance of the normal flora in the intestines. The result is often loose, watery stools known as antibiotic-associated diarrhea.
The idea behind using probiotics is that they may help populations of good bacteria recover more quickly and restore order to the intestines. There’s no good evidence that probiotics are helpful in otherwise healthy people. But earlier research has suggested they can be helpful in:
The best way to keep your normal flora in balance is to only take antibiotics when necessary.
(Harvard Health Pub.)
That’s the conclusion of a study just published in the Journal of the American Medical Association. A team of California-based researchers combined the results of 63 randomized trials pitting probiotics versus placebo among almost 12,000 men and women taking antibiotics. Those who took antibiotics plus probiotics were 42% less likely to develop diarrhea as those who got the placebo.
About one in three people who take antibiotics develop diarrhea. The symptoms usually start on the last day or two of antibiotic therapy, or a day or so after it has ended. The diarrhea is usually mild, with two to four loose stools per a lasting for a couple days. In most cases, it gets better quickly without treatment. That said, antibiotic-associated diarrhea makes some people very sick. The most severe form, called C. difficile colitis, can be life threatening.
Probiotics are live bacteria, yeast, and other microbes thought to be beneficial to human health. They’ve been widely promoted as a way to keep your body in balance. The evidence for many of these claims is slim. Perhaps the strongest evidence a benefit of probiotics is for antibiotic-associated diarrhea.
Antibiotics upset intestinal balance
Thousands of species of bacteria, yeast, and other microorganisms live on our skin, in our intestines, and on other body surfaces. They’re known as our “normal flora.” When it is in balance, these microbes stay put and many of them contribute to good health. Bacteria in the gut, for example, help break down food.Antibiotics kill these “good” microbes along with bacteria that are causing an infection. This upsets the balance of the normal flora in the intestines. The result is often loose, watery stools known as antibiotic-associated diarrhea.
The idea behind using probiotics is that they may help populations of good bacteria recover more quickly and restore order to the intestines. There’s no good evidence that probiotics are helpful in otherwise healthy people. But earlier research has suggested they can be helpful in:
- treating recurrent or persistent C. difficile colitis, when repeated courses of other therapies have not been successful
- preventing complications from pancreatitis
- decreasing persistent or recurring vaginal yeast infections
Not a cure-all
Although the results of this study sound impressive, I won’t be recommending probiotics every time I write a prescription for antibiotic. But I will advise some of my patients to try a probiotic. They include:- people who have had antibiotic-associated diarrhea in the past. This is especially true for those that have had a C. difficile infection.
- people who must take antibiotics for more than 10 days. (Other doctors might use more than 5 days).
- people who have switched from one antibiotic to another over a relatively short period of time.
- Which probiotics are the most effective in preventing and treating antibiotic associated diarrhea?
- Which antibiotics are more likely to cause diarrhea?
The medical bottom line
Antibiotics are wonderful medicines. But this study of probiotics and many other studies show they also have a dark side. The best way to avoid antibiotic-associated diarrhea is to limit your use of antibiotics. For example, you likely don’t need an antibiotic for an uncomplicated ear or sinus infection or bronchitis. Most often the culprits are viruses, which don’t respond to antibiotics anyway.The best way to keep your normal flora in balance is to only take antibiotics when necessary.
(Harvard Health Pub.)
May 4, 2012
Apr 26, 2012
Mar 31, 2012
CREAFEM FOOD CONSULTING®
WHAT WE DO ?
*Food Export; know-how to the Middle East. Guide for Companies wishing
to export the food products to Europe. Guide is including; EU laws and
regulations, recipe, packaging, process and quality requests.
*For food industries, in particular: innovative recipe and packaging design of new products to small and medium companies.
*Use of food remnants in the industry by creating new products and reduce production cost and waste.
*Helps to the company to make profitable their production.
Mar 2, 2012
CHOLESTEROL (Part 2)
GOOD FATS
Unsaturated fats are called good fats because they can improve blood
cholesterol levels, ease inflammation, stabilize heart rhythms, and play
a number of other beneficial roles. Unsaturated fats are predominantly
found in foods from plants, such as vegetable oils, nuts, and seeds.
They are liquids at room temperature.
There are two types of unsaturated fats:
- Monounsaturated fats are found in high concentrations in olive, peanut, and canola oils; avocados; nuts such as almonds, hazelnuts, and pecans; and seeds such as pumpkin and sesame seeds.
- Polyunsaturated fats are found in high concentrations in sunflower, corn, soybean, and flaxseed oils, and also in foods such as walnuts, flax seeds, and fish; canola oil, though higher in monounsaturated fat, is also a good source of polyunsaturated fat. Omega-3 fats, which are fast becoming the darling of the supplement industry, are an important type of polyunsaturated fat. The body can't make these, so they must come from food. An excellent way to get omega-3 fats is by eating fish two or three times a week. Good plant sources of omega-3 fats include chia seeds (sold as Salvia), flax seeds, walnuts, and oils such as flaxseed, canola, and soybean.
CHOLESTEROL (Part 1)
Cholesterol, a soft, waxy substance found in the bloodstream and an essential component of cell membranes, assists in various biological functions. There are two basic types of cholesterol—high-density lipoprotein and low-density lipoprotein—both of which are made by the body and obtained via the diet. When low-density lipoprotein cholesterol circulates in abundance in the bloodstream, it can clog arteries, increasing risk for cardiovascular disease. High-density lipoprotein helps keep low-density lipoprotein from getting lodged into artery walls.
Recently, scientists identified a number of other “bad" cholesterol molecules, including very low-density lipoprotein and intermediate-density lipoprotein . To take these into account, medical authorities and researchers have started referring to a new measurement, non-high-density lipoprotein cholesterol, which is basically total cholesterol minus high-density lipoprotein. This is important, because scientists now believe that a healthy level of high-density lipoprotein may also protect against cardiovascular disease, while low levels have actually been shown to increase risk.
Recently, scientists identified a number of other “bad" cholesterol molecules, including very low-density lipoprotein and intermediate-density lipoprotein . To take these into account, medical authorities and researchers have started referring to a new measurement, non-high-density lipoprotein cholesterol, which is basically total cholesterol minus high-density lipoprotein. This is important, because scientists now believe that a healthy level of high-density lipoprotein may also protect against cardiovascular disease, while low levels have actually been shown to increase risk.
Almost all foods contain some fat. Even quintessential fat-free foods
like carrots and lettuce contain small amounts of this nutrient. That's a
testament to how important fats are for life. Fat provides a terrific
source of energy as well as a great depot for storing it. It is an
important part of cell membranes, helping govern what gets into cells
and what comes out. The body uses cholesterol as the starting point to
make estrogen, testosterone, vitamin D, and other vital compounds. Fats
are also biologically active molecules that can influence how muscles
respond to insulin's "open up for sugar" signal; different types of fats
can also fire up or cool down inflammation.
Low-density lipoproteins carry cholesterol from the liver to the
rest of the body. Cells latch onto these particles and extract fat and
cholesterol from them. When there is too much low-density lipoproteins cholesterol in the
blood, these particles can form deposits in the walls of the coronary
arteries and other arteries throughout the body. Such deposits, called
plaque, can narrow arteries and limit blood flow. When plaque breaks
apart, it can cause a heart attack or stroke. Because of this, low-density lipoproteins
cholesterol is often referred to as bad, or harmful, cholesterol.
High-density lipoproteins scavenge cholesterol from the
bloodstream, from low-density lipoproteins, and from artery walls and ferry it back to the
liver for disposal. Think of high-density lipoprotein as the garbage trucks of the
bloodstream. High-density lipoprotein cholesterol is often referred to as good, or
protective, cholesterol.
Triglycerides make up most of the fat that you eat and that travels
through the bloodstream. As the body's main vehicle for transporting
fats to cells, triglycerides are important for good health. But as is
the case for so many things, an excess of triglycerides can be
unhealthy.
Feb 28, 2012
Feb 27, 2012
FOOD SAFETY
To reduce your risk for listeriosis and other foodborne illnesses, everyone should follow these 4 Simple Steps.
Tips in bold are especially important in preventing listeriosis.
Step 1 – CLEAN
Step 2 – SEPARATE
Step 3 – COOK
Step 4 – CHILL
Tips in bold are especially important in preventing listeriosis.
Step 1 – CLEAN
(Wash hands and surfaces often)
- Wash hands with warm water and soap for 20 seconds before and after handling food, and after using the bathroom, changing diapers, or handling pets.
- Wash cutting boards, dishes, utensils and countertops with hot water and soap after they come in contact with raw meat, poultry, seafood, and eggs.
- Rinse raw produce in water. Don't use soap or detergents. If necessary, use a small produce brush to remove surface dirt
- Wipe up spills in the refrigerator immediately and clean the refrigerator regularly.
Step 2 – SEPARATE
(Don't cross-contaminate)
- Raw meat, poultry, and seafood can contain harmful bacteria, so keep these foods separate from other foods in your grocery cart and in your refrigerator.
- If possible, use one cutting board for raw meat, poultry, and seafood and another one for produce.
- Wash cutting boards, dishes, and utensils with hot water and soap after they come in contact with raw meat, poultry, seafood, and eggs.
- Use separate plates for cooked or ready-to-eat foods and other plates for raw foods.
Step 3 – COOK
(Cook foods to a safe internal temperature)
- Heating foods to the right temperature kills harmful bacteria, so cook meat, poultry, and seafood thoroughly. Use a clean food thermometer to check for proper temperatures.
- People in the at-risk groups should not eat hot dogs and luncheon meats – unless they're reheated until steaming hot. They also should not eat refrigerated smoked seafood – unless it's in a cooked dish, such as a casserole.
- Cook eggs until the yolk and white are firm. If you use recipes in which eggs remain raw or only partially cooked, use pasteurized eggs; cook to 160 °F (71 °C).
- Fish should be opaque and flake easily with a fork.
- Reheat leftovers to 165 °F (74 °C). Bring sauces, soups, and gravy to a boil when reheating.
Step 4 – CHILL
(Refrigerate promptly)
- Your refrigerator should register at 40 °F (4 °C) or below and the freezer at 0 °F (-18 °C). Place a refrigerator thermometer in the refrigerator, and check the temperature periodically. A second thermometer should go in the freezer.
- Store perishable foods that are precooked or ready-to-eat in your refrigerator at 40 °F (4 °C) or below, and eat them as soon as possible. Don't keep them in the refrigerator too long.
- Refrigerate or freeze perishables, prepared food, and leftovers within two hours of eating or preparation, or after one hour in temperatures over 90 °F.
LISTERIOSIS AT-RISK GROUPS
| Who's At Risk? | Why? |
|---|---|
| Pregnant women |
|
| Unborn babies and newborns |
|
| Older adults |
|
| Other people with weakened imune systems (transplant patients and those with HIV/AIDS, cancer, diabetes, kidney disease, etc.) |
|
LISTERIA-KEEP OUT OF YOUR KITCHEN
If you eat food contaminated with bacteria called Listeria, you could get so sick that you have to be hospitalized. And for certain vulnerable people, the illness could be fatal.
Contaminated food can bring Listeria into the home. Unlike most bacteria, Listeria germs can grow and spread in the refrigerator. So if you unknowingly refrigerate Listeria-contaminated food, the germs could contaminate your refrigerator and spread to other foods there and increase the likelihood that you and your family will become sick.
Those most at risk for listeriosis—the illness caused by Listeria monocytogenes—include pregnant women, older adults and people with compromised immune systems and certain chronic medical conditions (such as HIV/AIDS, cancer, diabetes, kidney disease, and transplant patients). In pregnant women, listeriosis can cause miscarriage, stillbirth, and serious illness or death in newborn babies.
Recently, a multi-state outbreak of listeriosis tied to contaminated cantaloupes has caused illnesses and deaths. Listeria has also been linked to a variety of ready-to-eat foods, including unpasteurized milk and dairy products, Mexican-style or soft cheeses made with unpasteurized milk, processed deli meats, hot dogs, smoked seafood and store-prepared deli-salads.
Donald Zink, Ph.D, senior science advisor at FDA’s Center for Food Safety and Applied Nutrition, says FDA is aware of cases of foodborne illness caused by bacteria that can live in the kitchen and spread to foods.
Consumers are advised to wash all fruits and vegetables under running water just before eating, cutting or cooking, even if you plan to peel the produce first. Scrub firm produce such as melons and cucumbers with a clean produce brush.
To further protect yourself and your family from Listeria, follow these steps:
Contaminated food can bring Listeria into the home. Unlike most bacteria, Listeria germs can grow and spread in the refrigerator. So if you unknowingly refrigerate Listeria-contaminated food, the germs could contaminate your refrigerator and spread to other foods there and increase the likelihood that you and your family will become sick.
Those most at risk for listeriosis—the illness caused by Listeria monocytogenes—include pregnant women, older adults and people with compromised immune systems and certain chronic medical conditions (such as HIV/AIDS, cancer, diabetes, kidney disease, and transplant patients). In pregnant women, listeriosis can cause miscarriage, stillbirth, and serious illness or death in newborn babies.
Recently, a multi-state outbreak of listeriosis tied to contaminated cantaloupes has caused illnesses and deaths. Listeria has also been linked to a variety of ready-to-eat foods, including unpasteurized milk and dairy products, Mexican-style or soft cheeses made with unpasteurized milk, processed deli meats, hot dogs, smoked seafood and store-prepared deli-salads.
Donald Zink, Ph.D, senior science advisor at FDA’s Center for Food Safety and Applied Nutrition, says FDA is aware of cases of foodborne illness caused by bacteria that can live in the kitchen and spread to foods.
Consumers are advised to wash all fruits and vegetables under running water just before eating, cutting or cooking, even if you plan to peel the produce first. Scrub firm produce such as melons and cucumbers with a clean produce brush.
To further protect yourself and your family from Listeria, follow these steps:
Keep Refrigerated Foods Cold
Chilling food properly is an important way of reducing risk of Listeria infection. Although Listeria can grow at refrigeration temperatures, it grows more slowly at refrigerator temperatures of 40 degrees F or less.- Keep your refrigerator at 40 degrees F or lower and the freezer at 0 degrees F or lower.
- Wrap or cover foods with a sheet of plastic wrap or foil or put foods in plastic bags or clean covered containers before you place them in the refrigerator. Make certain foods do not leak juices onto other foods.
- Place an appliance thermometer, such as a refrigerator thermometer, in the refrigerator, and check the temperature periodically. Adjust the refrigerator temperature control, if necessary, to keep foods as cold as possible without causing them to freeze. Place a second thermometer in the freezer to check the temperature there.
- Use precooked and ready-to-eat foods as soon as you can. The longer they are stored in the refrigerator, the more chance Listeria has to grow.
"If you have leftovers in your refrigerator, it’s best to throw them out after three days, just to be sure,” says Zink. “It's better to be safe than sorry."
Clean Refrigerator Regularly
Listeria can contaminate other food through spills in the refrigerator.- Clean up all spills in your refrigerator right away—especially juices from hot dog and lunch meat packages, raw meat, and raw poultry. Consider using paper towels to avoid transferring germs from a cloth towel.
- Clean the inside walls and shelves of your refrigerator with warm water and liquid soap, then rinse. As an added measure of caution, you can sanitize your refrigerator monthly using the same procedures described below for kitchen surfaces.
Clean Hands and Kitchen Surfaces Often
Listeria can spread from one surface to another.- Thoroughly wash food preparation surfaces with warm, soapy water. As an added precaution you should sanitize clean surfaces by using any of the kitchen surface sanitizer products available from grocery stores, being careful to follow label directions.
- A cutting board should be washed with warm, soapy water after each use. Nonporous acrylic, plastic, or glass boards can be washed in a dishwasher.
- Dish cloths, towels and cloth grocery bags should be washed often in the hot cycle of your washing machine.
- It’s also important, to wash hands with warm water and soap for at least 20 seconds before and after handling food.
GRAPEFRUIT JUICE AND MEDICINE MAY NOT MIX !
Grapefruit juice can be part of a healthful diet—most of the time. It
has vitamin C and potassiu—substances your body needs to work
properly.
But it isn’t good for you when it affects the way your medicines work.
Grapefruit juice and fresh grapefruit can interfere with the action of some prescription drugs, as well as a few non-prescription drugs.
This interaction can be dangerous, says Shiew Mei Huang, acting director of the Food and Drug Administration’s Office of Clinical Pharmacology. With most drugs that interact with grapefruit juice, “the juice increases the absorption of the drug into the bloodstream,” she says. “When there is a higher concentration of a drug, you tend to have more adverse events.”
For example, if you drink a lot of grapefruit juice while taking certain statin drugs to lower cholesterol, too much of the drug may stay in your body, increasing your risk for liver damage and muscle breakdown that can lead to kidney failure.
Drinking grapefruit juice several hours before or several hours after you take your medicine may still be dangerous, says Huang, so it’s best to avoid or limit consuming grapefruit juice or fresh grapefruit when taking certain drugs.
Examples of some types of drugs that grapefruit juice can interact with are:
Too High or Too Low Drug Levels
Many drugs are broken down (metabolized) with the help of a vital enzyme called CYP3A4 in the small intestine. Certain substances in grapefruit juice block the action of CYP3A4, so instead of being metabolized, more of the drug enters the bloodstream and stays in the body longer. The result: potentially dangerous levels of the drug in your body.
The amount of the CYP3A4 enzyme in the intestine varies from one person to another, says Huang. Some people have a lot, and others have just a little—so grapefruit juice may affect people differently when they take the same drug.
While scientists have known for several decades that grapefruit juice can cause a potentially toxic level of certain drugs in the body, Huang says more recent studies have found that the juice has the opposite effect on a few other drugs.
“Grapefruit juice reduces the absorption of fexofenadine,” says Huang, decreasing the effectiveness of the drug. Fexofenadine (brand name Allegra) is available in both prescription and non-prescription forms to relieve symptoms of seasonal allergies. Fexofenadine may also be less effective if taken with orange or apple juice, so the drug label states “do not take with fruit juices.”
Why this opposite effect?
It involves the transportation of drugs within the body rather than their metabolism, explains Huang. Proteins in the body known as drug transporters help move a drug into cells for absorption.
Substances in grapefruit juice block the action of a specific group of transporters. As a result, less of the drug is absorbed and it may be ineffective, Huang says.
When a drug sponsor applies to FDA for approval of a drug, the sponsor submits data on how its drug is absorbed, metabolized and transported says Huang. “Then we can decide how to label the drug.”
FDA has required some prescription drugs to carry labels that warn against consuming grapefruit juice or fresh grapefruit while using the drug, says Huang. And the agency’s current research into drug and grapefruit juice interaction may result in label changes for other drugs as well.
(http://www.fda.gov/ForConsumers/ConsumerUpdates/ucm292276.htm)
But it isn’t good for you when it affects the way your medicines work.
Grapefruit juice and fresh grapefruit can interfere with the action of some prescription drugs, as well as a few non-prescription drugs.
This interaction can be dangerous, says Shiew Mei Huang, acting director of the Food and Drug Administration’s Office of Clinical Pharmacology. With most drugs that interact with grapefruit juice, “the juice increases the absorption of the drug into the bloodstream,” she says. “When there is a higher concentration of a drug, you tend to have more adverse events.”
For example, if you drink a lot of grapefruit juice while taking certain statin drugs to lower cholesterol, too much of the drug may stay in your body, increasing your risk for liver damage and muscle breakdown that can lead to kidney failure.
Drinking grapefruit juice several hours before or several hours after you take your medicine may still be dangerous, says Huang, so it’s best to avoid or limit consuming grapefruit juice or fresh grapefruit when taking certain drugs.
Examples of some types of drugs that grapefruit juice can interact with are:
- some statin drugs to lower cholesterol, such as Zocor (simvastatin), Lipitor (atorvastatin) and Pravachol (pravastatin)
- some blood pressure-lowering drugs, such as Nifediac and Afeditab (both nifedipine)
- some organ transplant rejection drugs, such as Sandimmune and Neoral (both cyclosporine)
- some anti-anxiety drugs, such as BuSpar (buspirone)
- some anti-arrhythmia drugs, such as Cordarone and Nexterone (both amiodarone)
- some antihistamines, such as Allegra (fexofenadine)
Too High or Too Low Drug Levels
Many drugs are broken down (metabolized) with the help of a vital enzyme called CYP3A4 in the small intestine. Certain substances in grapefruit juice block the action of CYP3A4, so instead of being metabolized, more of the drug enters the bloodstream and stays in the body longer. The result: potentially dangerous levels of the drug in your body.
The amount of the CYP3A4 enzyme in the intestine varies from one person to another, says Huang. Some people have a lot, and others have just a little—so grapefruit juice may affect people differently when they take the same drug.
While scientists have known for several decades that grapefruit juice can cause a potentially toxic level of certain drugs in the body, Huang says more recent studies have found that the juice has the opposite effect on a few other drugs.
“Grapefruit juice reduces the absorption of fexofenadine,” says Huang, decreasing the effectiveness of the drug. Fexofenadine (brand name Allegra) is available in both prescription and non-prescription forms to relieve symptoms of seasonal allergies. Fexofenadine may also be less effective if taken with orange or apple juice, so the drug label states “do not take with fruit juices.”
Why this opposite effect?
It involves the transportation of drugs within the body rather than their metabolism, explains Huang. Proteins in the body known as drug transporters help move a drug into cells for absorption.
Substances in grapefruit juice block the action of a specific group of transporters. As a result, less of the drug is absorbed and it may be ineffective, Huang says.
When a drug sponsor applies to FDA for approval of a drug, the sponsor submits data on how its drug is absorbed, metabolized and transported says Huang. “Then we can decide how to label the drug.”
FDA has required some prescription drugs to carry labels that warn against consuming grapefruit juice or fresh grapefruit while using the drug, says Huang. And the agency’s current research into drug and grapefruit juice interaction may result in label changes for other drugs as well.
Tips for Consumers
- Ask your pharmacist or other health care professional if you can have fresh grapefruit or grapefruit juice while using your medication. If you can’t, you may want to ask if you can have other juices with the medicine.
- Read the Medication Guide or patient information sheet that comes with your prescription medicine to find out if it could interact with grapefruit juice. Some may advise not to take the drug with grapefruit juice. If it’s OK to have grapefruit juice, there will be no mention of it in the guide or information sheet.
- Read the Drug Facts label on your non-prescription medicine, which will let you know if you shouldn’t have grapefruit or other fruit juices with it.
- If you must avoid grapefruit juice with your medicine, check the label of bottles of fruit juice or drinks flavored with fruit juice to make sure they don’t contain grapefruit juice.
- Seville oranges (often used to make orange marmalade) and tangelos (a cross between tangerines and grapefruit) affect the same enzyme as grapefruit juice, so avoid these fruits as well if your medicine interacts with grapefruit juice.
(http://www.fda.gov/ForConsumers/ConsumerUpdates/ucm292276.htm)
Feb 26, 2012
Feb 20, 2012
FOOD ALLERGY-HISTAMINE AND HEADACHE
Headache can be induced dose-dependently by histamine in healthy persons as well as in patients with migraine.Histamine-induced headache is a vascular headache caused mainly by nitrate monoxide. Histamine releases endothelial nitrate monoxide upon stimulation of H1R, which is also expressed in the large intracranial arteries. In migraine patients, plasma histamine concentrations have been shown to be elevated both during headache attacks and during symptom-free periods. An increase in the number of brain mast cells is associated with pathologic conditions such as migraine, cluster headache, and multiple sclerosis. Many migraine patients have histamine intolerance evidenced by reduced diamine oxidase activity, triggering of headache by food rich in histamine (eg, long-ripened cheese or wine), and the alleviation of headache (ie, disappearance of symptoms) under a histamine-free diet and therapy with antihistamines.
Foods rich in histamine1
Fish (frozen/smoked or salted/canned)
Mackerel
Herring
Sardine
Tuna
Cheese
Gouda
Camembert
Cheddar
Emmental
Swiss
Parmesan
Meat
Fermented sausage
Salami
Fermented ham
Vegetables
Sauerkraut
Spinach
Eggplant
Tomato ketchup
Red wine vinegar
Alcohol
White wine
Red wine
Top-fermented beer
Bottom-fermented beer
Champagne
(Am J Clin Nutr 2007;85:1185–96.)
FOOD ALLERGY-HISTAMINE AND HISTAMINE INTOLERANCE
Histamine intolerance results from a disequilibrium of accumulated histamine and the capacity for histamine degradation. Histamine is a biogenic amine that occurs to various degrees in many foods. In healthy persons, dietary histamine can be rapidly detoxified by amine oxidases, whereas persons with low amine oxidase activity
are at risk of histamine toxicity. Diamine oxidase (DAO) is the main enzyme for the metabolism of ingested histamine. It has been proposed that Diamine oxidase, when functioning as a secretory protein, may be responsible for scavenging extracellular histamine after mediator release. Conversely, histamine N-methyltransferase, the other important enzyme inactivating histamine, is a cytosolic protein that can convert histamine only in the intracellular space of cells. An impaired histamine degradation based on reduced Diamine oxidase activity and the resulting histamine excess may cause numerous symptoms mimicking an allergic reaction. The ingestion of histamine-rich food or of alcohol or drugs that release histamine or block Diamine oxidase may provoke diarrhea, headache, rhinoconjunctival symptoms, asthma, hypotension, arrhythmia, urticaria, pruritus, flushing, and other conditions in patients with histamine intolerance. Symptoms can be reduced by a histamine-free diet or be eliminated by antihistamines.
are at risk of histamine toxicity. Diamine oxidase (DAO) is the main enzyme for the metabolism of ingested histamine. It has been proposed that Diamine oxidase, when functioning as a secretory protein, may be responsible for scavenging extracellular histamine after mediator release. Conversely, histamine N-methyltransferase, the other important enzyme inactivating histamine, is a cytosolic protein that can convert histamine only in the intracellular space of cells. An impaired histamine degradation based on reduced Diamine oxidase activity and the resulting histamine excess may cause numerous symptoms mimicking an allergic reaction. The ingestion of histamine-rich food or of alcohol or drugs that release histamine or block Diamine oxidase may provoke diarrhea, headache, rhinoconjunctival symptoms, asthma, hypotension, arrhythmia, urticaria, pruritus, flushing, and other conditions in patients with histamine intolerance. Symptoms can be reduced by a histamine-free diet or be eliminated by antihistamines.
(Am J Clin Nutr 2007;85:1185–96)
Jan 15, 2012
CANCER AND CHLOROPHYLL
Oregon State University (OSU) researchers have discovered chlorophyll
in green vegetables can help protect against modest carcinogen exposure
levels commonly found in the environment. The downside is chlorophyll
increased the number of tumors when carcinogens were at a high exposure
levels. Results from the study, which was supported by the National
Institutes of Health (NIH), were published in the journal Food and Chemical Toxicology (2012 Feb.;50(2):341-352).
While their earlier studies found positive results with chlorophyll in both mice and trout, the scientists used 12,360 rainbow trout as laboratory models in this study, explaining using rodents is much more expensive, which requires the use of fewer specimens and higher carcinogen exposures. The design of this study featured a dose–dose matrix to examine chlorophyll-mediated effects on carcinogen-induced DNA adduct formation (biomarker of exposure and potential cancer development), tumor incidence, tumor multiplicity and changes in gene regulation in the trout. Researchers administered dietary chlorophyll (0 to 4000 ppm) and carcinogen (0 to 25 ppm of DBC) for up to four weeks.
They found the carcinogen dose-dependently changed gene expression in the fish that were fixed by the chlorophyll; there were no changes when chlorophyll was given without the carcinogen. WHen given to animals also exposed to the carcinogen, the chlorophyll reduced tumor multiplicity and incidence that had risen due to carcinogenic exposure. However, when carcinogenic exposure was at high levels, chlorophyll failed to inhibit multiplicity and incidence. The researchers noted, " This finding questions the human relevance of chemoprevention studies carried out at high carcinogen doses that are not proven to lie within a linear, or at least monotonic, endpoint dose–response range."
Tammie McQuistan, one of the researchers, said there’s considerable evidence in epidemiologic and other clinical studies with humans that chlorophyll and its derivative, chlorophyllin, can protect against cancer. “This study, like others before it, found that chlorophyll can reduce tumors, up to a point,” she said. “But at very high doses of the same carcinogen, chlorophyll actually made the problem worse. This questions the value of an approach often used in studying cancer-causing compounds.”
The researchers explained traditional research involving small numbers of animals fed very high doses of a carcinogen might conclude that chlorophyll has the potential to increase human cancer risk. However, this current study, combined with other evidence, found a more refined and telling result. They noted the results showed the protective mechanism of chlorophyll is fairly simple— it just binds with and sequesters carcinogens within the gastrointestinal tract until the dangerous chemicals are eliminated from the body.
“The central assumption of such experiments is that intervention effects at high carcinogen dose will apply equally at lower carcinogen doses,” the researchers wrote. “Contrary to the usual assumption, the outcomes in the major target organ were strikingly dependent on carcinogen dose.”
(Corvallis, Ore-Natural Products)
While their earlier studies found positive results with chlorophyll in both mice and trout, the scientists used 12,360 rainbow trout as laboratory models in this study, explaining using rodents is much more expensive, which requires the use of fewer specimens and higher carcinogen exposures. The design of this study featured a dose–dose matrix to examine chlorophyll-mediated effects on carcinogen-induced DNA adduct formation (biomarker of exposure and potential cancer development), tumor incidence, tumor multiplicity and changes in gene regulation in the trout. Researchers administered dietary chlorophyll (0 to 4000 ppm) and carcinogen (0 to 25 ppm of DBC) for up to four weeks.
They found the carcinogen dose-dependently changed gene expression in the fish that were fixed by the chlorophyll; there were no changes when chlorophyll was given without the carcinogen. WHen given to animals also exposed to the carcinogen, the chlorophyll reduced tumor multiplicity and incidence that had risen due to carcinogenic exposure. However, when carcinogenic exposure was at high levels, chlorophyll failed to inhibit multiplicity and incidence. The researchers noted, " This finding questions the human relevance of chemoprevention studies carried out at high carcinogen doses that are not proven to lie within a linear, or at least monotonic, endpoint dose–response range."
Tammie McQuistan, one of the researchers, said there’s considerable evidence in epidemiologic and other clinical studies with humans that chlorophyll and its derivative, chlorophyllin, can protect against cancer. “This study, like others before it, found that chlorophyll can reduce tumors, up to a point,” she said. “But at very high doses of the same carcinogen, chlorophyll actually made the problem worse. This questions the value of an approach often used in studying cancer-causing compounds.”
The researchers explained traditional research involving small numbers of animals fed very high doses of a carcinogen might conclude that chlorophyll has the potential to increase human cancer risk. However, this current study, combined with other evidence, found a more refined and telling result. They noted the results showed the protective mechanism of chlorophyll is fairly simple— it just binds with and sequesters carcinogens within the gastrointestinal tract until the dangerous chemicals are eliminated from the body.
“The central assumption of such experiments is that intervention effects at high carcinogen dose will apply equally at lower carcinogen doses,” the researchers wrote. “Contrary to the usual assumption, the outcomes in the major target organ were strikingly dependent on carcinogen dose.”
(Corvallis, Ore-Natural Products)
Jan 10, 2012
The U.S. Department of Agriculture is ready to approve a new corn variety that is genetically modified by Dow Chemical to be resistant to the herbicide 2,4-D.
USDA Announces Biotechnology Regulatory Actions
WASHINGTON, Dec. 21, 2011--The U.S. Department of Agriculture's (USDA) Animal and Plant Health Inspection Service (APHIS) is announcing four regulatory notices and supporting scientific evaluations related to the agency’s oversight of genetically-engineered plants. Three notices will be published in the Federal Register on Dec. 27 and a fourth was published on Dec. 16.
APHIS has made a determination of nonregulated status of two separate items: corn genetically engineered to better withstand drought conditions, as well as a soybean which has been genetically engineered to have tolerance to the herbicide glyphosate and produce higher levels of oleic acid. In addition, APHIS has prepared plant pest risk assessments (PPRA) and draft environmental assessments (EA) to address requests from developers seeking determinations of nonregulated status of two separate items: a soybean that has been genetically engineered to produce an omega-3 fatty acid and corn that has been genetically engineered to be resistant to the herbicide
2,4-D.
MON 87460 Corn: Nonregulated Status
This is APHIS’ first determination of nonregulated status of a product that has been genetically engineered to increase drought tolerance. Monsanto Co. petitioned APHIS for a determination of nonregulated status of its corn line designated as event MON 87460 in 2009. In a notice published in the Federal Register on May 11, 2011, APHIS announced the availability of the Monsanto petition, a PPRA, and a draft environmental assessment (EA) for public comment. APHIS solicited comments on the petition; whether the subject corn is unlikely to pose a plant pest risk; the draft EA; and the PPRA, for 60 days, ending July 11, 2011.
Based on the data submitted by Monsanto with its petition for deregulation, APHIS’ risk assessment and evaluation of scientific information, and review of the public comments received, APHIS has determined that the product is unlikely to present a plant pest risk and is therefore determining nonregulated status. Further information on this product and APHIS’ determination can be found at www.aphis.usda.gov/biotechnology/news.shtml.
MON 87705 Soybean: Nonregulated Status
Monsanto Co. also petitioned APHIS for a determination of nonregulated status of a soybean line designated as event MON 87705 in 2009. This soybean was genetically engineered to have a modified fatty acid profile and for tolerance to the herbicide glyphosate. In response, APHIS prepared a PPRA and an EA and made both documents, as well as Monsanto’s petition, available for public comment on June 28, 2011. Through its evaluation of Monsanto’s petition, the PPRA, and review of public comments received, APHIS has determined that the soybean is unlikely to pose a plant pest risk. The soybean is therefore no longer subject to APHIS regulation; the agency published its determination of nonregulated status of this event in the Federal Register on Dec. 16, 2011. Further information on this determination can be found at www.aphis.usda.gov/biotechnology/news.shtml.
MON 87769 Soybean: For Public Comment
APHIS is also announcing today that it has prepared a PPRA and a draft EA to address a request from Monsanto Co. seeking a determination of nonregulated status of its MON 87769 soybean. This soybean has been genetically engineered to produce stearidonic acid, an omega-3 fatty acid that helps to prevent a wide variety of adverse health conditions and not typically found in soybean oil.
APHIS' risk assessment indicates that MON 87769 is unlikely to pose a plant pest risk. APHIS is making available for public comment the Monsanto petition, the agency's PPRA, and the draft EA for the proposed determination of nonregulated status. These documents can be found at www.aphis.usda.gov/biotechnology/news.shtml; the public comment period will close on Feb. 27, 2012.
DAS-40278-9 Corn: For Public Comment
Finally, APHIS is also making available today a PPRA and a draft EA to address a request from Dow, Inc. seeking a determination of nonregulated status of its DAS-40278-9 corn. This corn has been genetically engineered to provide tolerance to 2,4-D and aryloxyphenoxypropionate (AOPP) acetyl coenzyme A carboxylase (ACCase) inhibitors, also known as “fop” herbicides. DAS-40278-9 corn has been field tested in the major corn growing regions of the continental United States as well as Hawaii.
APHIS’ risk assessment indicates that DAS-40278-9 corn is unlikely to pose a plant pest risk. APHIS is making available for public comment the Dow petition for nonregulated status, APHIS’ PPRA and draft EA. These documents can be found at www.aphis.usda.gov/biotechnology/news.shtml; the public comment period will close on Feb. 27, 2012.
WASHINGTON, Dec. 21, 2011--The U.S. Department of Agriculture's (USDA) Animal and Plant Health Inspection Service (APHIS) is announcing four regulatory notices and supporting scientific evaluations related to the agency’s oversight of genetically-engineered plants. Three notices will be published in the Federal Register on Dec. 27 and a fourth was published on Dec. 16.
APHIS has made a determination of nonregulated status of two separate items: corn genetically engineered to better withstand drought conditions, as well as a soybean which has been genetically engineered to have tolerance to the herbicide glyphosate and produce higher levels of oleic acid. In addition, APHIS has prepared plant pest risk assessments (PPRA) and draft environmental assessments (EA) to address requests from developers seeking determinations of nonregulated status of two separate items: a soybean that has been genetically engineered to produce an omega-3 fatty acid and corn that has been genetically engineered to be resistant to the herbicide
2,4-D.
MON 87460 Corn: Nonregulated Status
This is APHIS’ first determination of nonregulated status of a product that has been genetically engineered to increase drought tolerance. Monsanto Co. petitioned APHIS for a determination of nonregulated status of its corn line designated as event MON 87460 in 2009. In a notice published in the Federal Register on May 11, 2011, APHIS announced the availability of the Monsanto petition, a PPRA, and a draft environmental assessment (EA) for public comment. APHIS solicited comments on the petition; whether the subject corn is unlikely to pose a plant pest risk; the draft EA; and the PPRA, for 60 days, ending July 11, 2011.
Based on the data submitted by Monsanto with its petition for deregulation, APHIS’ risk assessment and evaluation of scientific information, and review of the public comments received, APHIS has determined that the product is unlikely to present a plant pest risk and is therefore determining nonregulated status. Further information on this product and APHIS’ determination can be found at www.aphis.usda.gov/biotechnology/news.shtml.
MON 87705 Soybean: Nonregulated Status
Monsanto Co. also petitioned APHIS for a determination of nonregulated status of a soybean line designated as event MON 87705 in 2009. This soybean was genetically engineered to have a modified fatty acid profile and for tolerance to the herbicide glyphosate. In response, APHIS prepared a PPRA and an EA and made both documents, as well as Monsanto’s petition, available for public comment on June 28, 2011. Through its evaluation of Monsanto’s petition, the PPRA, and review of public comments received, APHIS has determined that the soybean is unlikely to pose a plant pest risk. The soybean is therefore no longer subject to APHIS regulation; the agency published its determination of nonregulated status of this event in the Federal Register on Dec. 16, 2011. Further information on this determination can be found at www.aphis.usda.gov/biotechnology/news.shtml.
MON 87769 Soybean: For Public Comment
APHIS is also announcing today that it has prepared a PPRA and a draft EA to address a request from Monsanto Co. seeking a determination of nonregulated status of its MON 87769 soybean. This soybean has been genetically engineered to produce stearidonic acid, an omega-3 fatty acid that helps to prevent a wide variety of adverse health conditions and not typically found in soybean oil.
APHIS' risk assessment indicates that MON 87769 is unlikely to pose a plant pest risk. APHIS is making available for public comment the Monsanto petition, the agency's PPRA, and the draft EA for the proposed determination of nonregulated status. These documents can be found at www.aphis.usda.gov/biotechnology/news.shtml; the public comment period will close on Feb. 27, 2012.
DAS-40278-9 Corn: For Public Comment
Finally, APHIS is also making available today a PPRA and a draft EA to address a request from Dow, Inc. seeking a determination of nonregulated status of its DAS-40278-9 corn. This corn has been genetically engineered to provide tolerance to 2,4-D and aryloxyphenoxypropionate (AOPP) acetyl coenzyme A carboxylase (ACCase) inhibitors, also known as “fop” herbicides. DAS-40278-9 corn has been field tested in the major corn growing regions of the continental United States as well as Hawaii.
APHIS’ risk assessment indicates that DAS-40278-9 corn is unlikely to pose a plant pest risk. APHIS is making available for public comment the Dow petition for nonregulated status, APHIS’ PPRA and draft EA. These documents can be found at www.aphis.usda.gov/biotechnology/news.shtml; the public comment period will close on Feb. 27, 2012.
Jan 4, 2012
FOOD SUPPLEMENTS
Food supplements means foodstuffs the purpose of
which is to supplement a normal diet and which are concentrated sources
of nutrients or other substances with a nutritional or physiological
effect, alone or in combination.
The legislation "European Parliament directive 2002/46/EC" ,specifies that they are “marketed in dose form, namely forms such as capsules, pellets, tablets, pills and other similar forms, sachets of powder, liquids in ampules , drop dispensing bottles, and other similar forms of liquids and powders designed to be taken in small measured doses”.The regulations stipulate the gradual establishment of a positive list of ingredients authorized for the manufacturing of food supplements.
There are food supplements made from plants, vitamins, minerals and other substances used for a wide variety of purposes including nutrition, weight-loss, energy, digestion, beauty, the treatment of menopause and the cardiovascular system.
However, unlike medication, the marketing of food supplements does not require an individual marketing authorisation based on the evaluation of an industrial application by an expert assessment body. The manufacturer is responsible for ensuring that the marketed product is safe and compliant with current standards and that it does not mislead the consumer.
Nutritional shortages and, a fortiori, deficiencies are extremely rare in the general population and primarily concern specific population groups (e.g. pregnant women, elderly people in homes, very low-income populations with little security). In these specific population groups, additional intake of vitamins, minerals and other nutrients through food supplements or enriched foods may be beneficial, but in these cases, consumers should rely on medical advice rather than making an unenlightened dietary decision for themselves. For the vast majority of the population, a balanced diet alone can provide all necessary nutrients.
Consumption of food supplements therefore has no proven advantages for most people, especially given that we lack studies showing they are safe when taken regularly and for an extended amount of time, and also that severe acute accidents which may be linked to their use have been reported.
In the case of food supplements containing vitamins and minerals, consumers may risk exceeding the tolerable upper intake levels when taking excessive doses.
In the case of food supplements made from plant extracts, the preparation's safety can be demonstrated only if its production and instructions for use are clearly defined. Botanical specificities (species, plant parts), the method used to extract active substances, batch homogeneity and potential contaminants are just some factors that can alter the final product's composition and therefore its properties.
The legislation "European Parliament directive 2002/46/EC" ,specifies that they are “marketed in dose form, namely forms such as capsules, pellets, tablets, pills and other similar forms, sachets of powder, liquids in ampules , drop dispensing bottles, and other similar forms of liquids and powders designed to be taken in small measured doses”.The regulations stipulate the gradual establishment of a positive list of ingredients authorized for the manufacturing of food supplements.
There are food supplements made from plants, vitamins, minerals and other substances used for a wide variety of purposes including nutrition, weight-loss, energy, digestion, beauty, the treatment of menopause and the cardiovascular system.
However, unlike medication, the marketing of food supplements does not require an individual marketing authorisation based on the evaluation of an industrial application by an expert assessment body. The manufacturer is responsible for ensuring that the marketed product is safe and compliant with current standards and that it does not mislead the consumer.
Nutritional shortages and, a fortiori, deficiencies are extremely rare in the general population and primarily concern specific population groups (e.g. pregnant women, elderly people in homes, very low-income populations with little security). In these specific population groups, additional intake of vitamins, minerals and other nutrients through food supplements or enriched foods may be beneficial, but in these cases, consumers should rely on medical advice rather than making an unenlightened dietary decision for themselves. For the vast majority of the population, a balanced diet alone can provide all necessary nutrients.
Consumption of food supplements therefore has no proven advantages for most people, especially given that we lack studies showing they are safe when taken regularly and for an extended amount of time, and also that severe acute accidents which may be linked to their use have been reported.
In the case of food supplements containing vitamins and minerals, consumers may risk exceeding the tolerable upper intake levels when taking excessive doses.
In the case of food supplements made from plant extracts, the preparation's safety can be demonstrated only if its production and instructions for use are clearly defined. Botanical specificities (species, plant parts), the method used to extract active substances, batch homogeneity and potential contaminants are just some factors that can alter the final product's composition and therefore its properties.
Dec 14, 2011
TRANS FATTY ACIDS
Trans fatty acids belong to
the lipid family and more specifically to the unsaturated fatty acids
group, (i.e. chemically speaking, they contain at least one double
bond). Their name is related to the fact that their double bond is
located in the 'trans' position.
These compounds can form in very different ways:
*Some trans fatty acids are said to be natural.
They are created in the stomachs of ruminants (cows, sheep) by bacteria
in these animals' rumens. The compounds then pass into the animals'
body fat and milk. As a result, they can be found in meat, milk and dairy products.
*Other trans fatty acids are artificial.
They are synthesized via industrial processes such as the hydrogenation
of vegetable oils. Fats can therefore be transformed from liquid to
solid state, which facilitates their use and storage and makes them less
sensitive to oxidation. *They can also form when vegetable oils are heated or cooked at high
temperatures, whether for industrial processing or domestic use.
The main dietary sources of natural trans fatty acids are dairy products and meat.
Artificial trans fatty acids are used in the food processing industry as stabilisers and preservatives. They make foods firmer and more stable, and therefore less likely to go stale.
Artificial trans fatty acids are used in the food processing industry as stabilisers and preservatives. They make foods firmer and more stable, and therefore less likely to go stale.
Epidemiological studies have shown that an excessive consumption of trans fatty acids (intake greater than 2% of total energy intake) is related to increased cardiovascular risk. Trans fatty acids can increase levels of "bad" cholesterol and decrease levels of "good" cholesterol.
OMEGA 3
Omega-3 fatty acids belong to the family of
polyunsaturated fatty acids (lipids) They are called "essential" as they
help cells to function properly. The
precursor of this family, alpha-linolenic acid (ALA), is called "vital"
as it is necessary for the human body to develop and function properly.
The body cannot make it itself however, and we must therefore get it
through our diet. The body uses ALA to make other omega-3 fatty acids,
particularly long-chain polyunsaturated fatty acids including
docosahexaenoic acid (DHA).
Foods rich in omega 3 come from land plants and some marine animals:
· walnuts, rapeseed, soy, flax, etc.· oily fish, such as salmon, tuna, mackerel, herring, sardine and anchovy. Note that farmed fish contains much less omega 3 than wild fish.
· walnuts, rapeseed, soy, flax, etc.· oily fish, such as salmon, tuna, mackerel, herring, sardine and anchovy. Note that farmed fish contains much less omega 3 than wild fish.
Scientific findings show that the consumption of omega 3 FAs can:· reduce blood pressure in people presenting hypertension· reduce the quantity of triglycerides in the blood, a type of lipid which can trigger heart disease if there are too many of them· reduce cardiovascular disease and mortality levels in people who have previously presented cardiovascular diseases.
To date, dietary reference intakes (DRIs) for omega-3
fatty acids have been defined for ALA and DHA and vary for different
population groups. For adults, the DRI for ALA is 2g/day for men and
1.6g/d for women. The DRI for DHA is 120mg/day for men and 100mg/day for
women.
Getting a balanced intake of omega 3 and omega 6 FAs, another family of essential FAs, is also important.
This is because both are metabolised by common enzymes with which they compete, and therefore means that consuming too much omega 6 will reduce omega 3 FA metabolisation.
As part of an overall diet, it is therefore recommended that the omega 3/omega 6 ratio be about 5, which means limiting omega 6 intake and maintaining or increasing adequate intake of omega 3.
Getting a balanced intake of omega 3 and omega 6 FAs, another family of essential FAs, is also important.
This is because both are metabolised by common enzymes with which they compete, and therefore means that consuming too much omega 6 will reduce omega 3 FA metabolisation.
As part of an overall diet, it is therefore recommended that the omega 3/omega 6 ratio be about 5, which means limiting omega 6 intake and maintaining or increasing adequate intake of omega 3.
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